株式会社 協同病理
Cluster of Differentiation (CD)
最終更新日:2010.1.16

■ C D ( Human ) ■
Cluster of Differentiation (白血球分化抗原)と呼ばれるもので種々の分化段階の白血球表面に発現する抗原です。これらの中には分化過程のある段階にのみ発現するものや特定の subsetにのみ発現しているものなどもあります。参考までに「主な分布」を示しましたが、実際にはもっと複雑です。なお、この欄の略号はCLL(chronic lympocytic leukemia),ALL(Acute lymphoblastic leukemia),ATL(Adult T cell leukemia),AML(Acute myeloblastic leukemia),HCL(Hairy cell leukemia), HD(Hodgkin disease)などの病名の他は B=B cell,T=T cell,NK=NK cell,Pl=血小板・巨核球,Gr=顆粒球,Mo=単球, Eo=好酸球,My=骨髄球,SC=幹細胞,Er=赤血球,End=血管内皮,Φ=マクロファージを示し、特に代表的なものには背景に色を付けました。また、−とあるものは白血球全般に広範囲に分布するものです。
CD No. 主な分布 別名 HOST CLONE名 適用
CD1a ThymicT,B,Langerhans cell T6 Mouse 010 P*
CD3 mature T T3 Mouse PS1 P*
CD3 mature T T3 Rabbit Poly P*
CD4 T helper/inducer,ATL,NK T4 Mouse 4B12 P*
CD5 T,B subset(B-CLL) T1,Leu1 Mouse 4C7 P*
CD8 T suppressor/cytotoxic,(NK) T8 Mouse C8/144B P*
CD9 B,Pl,Mo,Eo,(T),Glia cell,etc MRP-1 Mouse 72F6 F/P*
CD10 B,B-cALL,fibroblast,(Gr) CALLA,commonALL Mouse 56C6 P*
CD11a Gr,Mo,T,(B) IntegrinαL/β2 ,LFA-1 Mouse 38 F
CD11b Gr,Mo,(NK,T,B) IntegrinαM/β2,C3bi-R,
CR3,LeuCAMb,Mac-1
Mouse 44 F
CD11c HCL,Φ,Mo,(Gr) p150/95 Mouse 3.9 F
CD11c HCL,Φ,Mo,(Gr) p150/95 Mouse 3.9 F
CD14 Mo,Φ,My,Gr,(AMMoL)   Mouse 7 P*
CD15 HD(RS)),Gr,Mo,AML,(Epithel) Lex,3-FAL,X-hapten Mouse BY87 P*
CD15s Gr,Mo,AML,(Epithel) Sialyl Lewis X,s-LeX,SLEX Mouse KM-93 P
CD18 Gr,Mo,T/B Integrin β2,LFA-1β,MEM48,p150 Mouse MEM48 F
CD19 B,(Plasma) B4 Mouse 4G7/2E F
CD20 B
Mouse 7D1 P*
CD20cy B L26,SL26 Mouse L26 P
CD22 B,HCL BL-CAM Mouse FPC1 P*
CD23 B,EBV transform B IgE-Fc receptor,MHM6 Mouse MHM6 P*
CD25 activated T/B,Mo,ATL,HCL IL-2 receptor,TacAg Mouse Tr69 F
CD28 T,ATL Activated T Ag Mouse CD28.2 F
CD29 T/B,Mo,End,Muscle,(Gr) Integrinβ1 chain,VLA-β Mouse K20 F
CD30 HD(RS),T/B,ALCL,Mo,End Ki-1,Ber-H2 Mouse Ber-H2 P
CD31 Pl,Gr,End PECAM-1,gpIIa' Mouse HC1/6 F
CD31 Pl,Gr,End PECAM-1,gpIIa' Mouse 1A10 P*
CD31 Pl,Gr,End PECAM-1,gpIIa' Mouse JC/70A P*
CD34 SC,End Endothelial cell marker Mouse QBEND10 P
CD34 SC,End Endothelial cell marker Mouse NU-4A1 P
CD35 Er,Gr,B,Mo,NK C3b receptor,CR1 Mouse Ber-Mac-DR P*
CD38 Plasma,early B,Thymo,NK,Mo   Mouse AT13/5 P*
CD38 Plasma,early B,Thymo,NK,Mo   Mouse SPC32 P*
CD41 Pl gpUb/Va,Integrin β3 Mouse M148 F
CD42b Pl,End gpTb Mouse MM2/174 F
CD43 T,(B),Pl,End MT-1,Leukosialin Mouse X63 P
CD44 T,Gr,Mo,Er,(Epithel) HCAM,Hyalronate receptor,Pgp-1 Mouse F10-44-2 F
CD44v6 Epithel,(Meso),Gr,Mo,Er, CD44 exon variant 6 Mouse TFF-1 P*
CD45 T/B,Mo,Gr Leucocyte common antigen(LCA) Mouse X16/99 P
CD45RA B,Mo,(T) MB-1 Mouse X63 P
CD45RO T,(B),Mo UCHL-1,p180 Mouse UCHL-1 P
CD49a Pl,End,Mo, Laminin Collagen receptor,
Integrinα1/β1(VLAα1)
Mouse HP2B6 P*
CD49b Pl,End,Mo,fibroblast,(T) Collagen receptor gpTa/Ua,
Integrinα2/β1(VLA-2)
Mouse VM1 F
CD49d (B) Fibronectin receptor LPAM2,
Integrinα4/β1(VLA-4)
Mouse P4G9 F
CD49f Pl,Mo,(T),(Epithel) Laminin receptor,gpTc/Ua,
Integrinα6β1(VLA-6)
Mouse 4F10 F
CD50 -,(End) ICAM-3 Mouse KS128 F/P*
CD54 -,(End,Fibroblast) ICAM-1 Mouse 6.5B5 F/P*
CD54 -,(End,Fibroblast) ICAM-1 Mouse 23G12 P*
CD56 NK,(T),Neural cell NCAM,Leu-19,NKH-1 Mouse ERIC1 F
CD56 NK,(T),Neural cell NCAM,Leu-19,NKH-1 Mouse 186 P*
CD57 NK,(T),Neuroendocrine Leu-7,HNK-1 Mouse NK-1 P
CD61 Pl,Mo,End,(B),Mast cell gpVa,Integrinβ3(VLAβ3),
vitronectin receptor
Mouse 2f2 P*
CD61 Pl,Mo,End,(B),Mast cell gpVa,Integrinβ3(VLAβ3),
vitronectin receptor
Mouse PM6/13 F
CD62E End E-Selectin,ELAM1,LECAM-2 Mouse 1.2B6 F
CD62L - L-Selectin,LECAM-1,LAM-1,
Leu-8,TQ1, MEL14
Mouse FMCA6 F
CD62P Pl,End P-Selectin,LECAM-3,GMP-140,PADGEN Mouse AK6 F
CD66ce Gr,(Epithel) CEA,NCA Rabbit Poly P
CD68 Φ,Mo,Gr,Mast cell Kp-1 Mouse Kp-1 P
CD71 activated T/B Transferrin receptor Mouse 10F11 P*
CD79a B,(T) mb-1 protein Mouse 11E3 P*
CD80 B B7-1/BB-1 Mouse MAB104 P
CD81 Mo,T,B,NK,Eo,Pl TAPA-1 Mouse 1D6 P*
CD83 HD(RS),Langerhans cell,Dendric
Mouse 1H4b P*
CD95 My,activated T/B FAS,APO1 Rabbit Poly P
CD99 T,Thymocyte,Ewing sarcoma MIC2 Mouse HO36-1.1 P*
CD102 Mo,End ICAM-2 Mouse B-T1 P*
CD105 End Endoglin Mouse 4G11 P*
CD106 End VCAM-1,INCAM110 Mouse 1.G11B1 F
CD117 SC,(AML),Mast cell,etc SCFR(c-kit) Rabbit Poly P
CD124 T/B,SC IL-4R Mouse S4-56C9 P*
CD138 preB,Pl Syndecan-1 Mouse 5F7 P*
CD140a End,Φ,Mo,Pl PDGFRα Rabbit Poly P
CD140b End,Φ,Mo,(Gr) PDGFRβ Rabbit Poly P
CD141 End,Pl,Mo,(Gr) Thrombomodulin Mouse 1009 P*
CD178 CTL,NK,Φ FasL Mouse 5D1 P*
CD207 Langerhans cell Langerin Mouse 12D6 P*
CD235a Er,Erblast Glycophorin A Mouse JC159 P
CD254 Dendric cell RANKL,ODF,OPGL,TRANCE,TNFSF11 Rabbit Poly


■ CDs ■
CD1a
CD1a X400
CD2
CD2 X400
CD3
CD3 X400
CD4
CD4 X400
CD5
CD5 X400
CD7
CD7 X400
CD8
CD8 X400
CD9
CD9 凍結 肺 X400
CD10
CD10 X400
CD10
CD10 小腸 X400
CD11a
CD11a 凍結 X400
CD11b
CD11b 凍結 X400
CD11c
CD11c 凍結 X400
CD14
CD14 X400
CD15
CD15 Hodgkin X400
CD15s
CD15s X400
CD16
CD16 胃 X400
CD19
CD19 凍結 X400
CD20
CD20cy X100
CD22
CD22 X400
CD23
CD23 X400
CD25
CD25 ATL X400
CD29
CD29 X400
CD30
CD30 X400Hodgkin
CD31
CD31 血管 X400
CD33
CD33 骨髄 X400
CD34
CD34 胃GIST X400
CD35
CD35 X400
CD38
CD38 Myeloma X400
CD41
CD41 骨髄塗抹 X400
CD43
CD43 X40
CD44
CD44 X400
CD44v6
CD44v6 X400
CD45
CD45 X400
CD45RA
CD45RA X40
CD45RO
CD45RO X40
CD49d
CD49d 凍結 X400
CD54
CD54 X400
CD56
CD56 X400
CD57
CD57 X400
CD61
CD61 骨髄 X400
CD62E
CD62E 凍結結腸 X400
CD62L
CD62L 凍結結腸 X400
CD62P
CD62P 凍結結腸 X400
CD68
CD68 X400
CD79a
CD79a X400
CD83
CD83 X400
CD95
CD95 皮膚 X400
CD99
CD99 膵 X400
CD105
CD105 血管 X400
CD106
CD106 凍結血管 X400
CD117
CD117 乳癌 X400
CD124
CD124 脾臓 X400
CD140a
CD140a 甲状腺 X400
CD141
CD141 血管 X400
CD163
CD163 X400
CD178
CD178 皮膚 X400
CD207
CD207 皮膚 X400
CD235a
CD235a 骨髄 X400(X4)
CD254
CD254 凍結皮膚 X400(X4)